Molecular Cell Article
· PDF 檔案Molecular Cell Article The Mechanism of a Neurotransmitter:Sodium Symporter—Inward Release of Na+ and Substrate Is Triggered by Substrate in a Second Binding Site Lei Shi,1,2,7 Matthias Quick,3,6,7 Yongfang Zhao,3 Harel Weinstein,1,2 and Jonathan A. Javitch3,4,5,6,*
scVAE: variational auto-encoders for single-cell gene …
The bulk RNA-seq dataset of RSEM expected gene expression levels for human cancer cell samples from TCGA (Weinstein et al., 2013) was also modelled. On a GPU with 12 GB of memory, we cannot model the dataset using all genes with the optimal network
Predicting Cancer Drug Response using a Recommender …
(Weinstein et al., 2013; Zhang et al., 2011), the identification of cancer driver genes has with this pre-processing step leading to a loss of information on relative ranking of drugs within each cell-line. Recently, Wang et al. proposed a matrix could
Cell wall: 3OH-A 2 pm, Gly; Ara, Xyl; N-glycolyl Mur . Production: Antibiotic G-418, verdamicins and sisomicin [ 1125 ]. Publication(s) using this strain [ A14150 , A15482 ].
(Weinstein, et al., Science 1997; 275:343-349) GoMiner Addresses the question, “Now that I’ve done the gene expression experiment and identified a set of ‘interesting’ genes, what do …
Planaria: Genes for regeneration
These include specifying cell fate in the notochord and floorplate, structures that are crucial for axis formation in the developing embryo (Ang and Rossant, 1994; Weinstein et al., 1994), and controlling the function of adult neurons that produce dopamine (Stott et).
O, Weinstein B, et al. Activity of alemtuzumab monotherapy in treatment-naive, relapsed, and refractory severe et al. Late effects in hematopoietic cell transplant recipients with acquired severe aplastic anemia: a report from the late effects working
Antin JH, Weinstein HJ, Guinan EC, McCarthy P, Bierer BE, Gilliland DG, Parsons SK, Ballen KK, Rimm IJ, Falzarano G, et al. Recombinant human interleukin-1 receptor antagonist in the treatment of steroid-resistant graft-versus-host disease.
The scientific and ethical feasibility of immunity passports …
There is much debate about the use of immunity passports in the response to the COVID-19 pandemic. Some have argued that immunity passports are unethical and impractical, pointing to uncertainties relating to COVID-19 immunity, issues with testing, perverse incentives, doubtful economic benefits, privacy concerns, and the risk of discriminatory effects. We first review the scientific
How to make a functional β-cell
This high demand on β-cells frequently leads to β-cell malfunction, de-differentiation and death (Ashcroft and Rorsman, 2012; Talchai et al., 2012). The number of β-cells lost in Type 2 diabetes is unclear but can approach 60% (Butler et al., 2003; Rahier et al
Author: “Weinstein, I.B.”
Author: Weinstein, I.B., et al. ; Simirgiotis, M.J.; Adachi, S.;To, S.; Yang, H.; Reynertson, K.A.; Basile, M.J.; Gil, R.R.; Kennelly, E.J.; Show all 9 Authors Source
Harel Weinstein, D.Sc. – Weill Cornell Medicine – …
Harel Weinstein, D.Sc. is the Maxwell Upson Professor of Physiology and Biophysics and Chairman of the Department of Physiology and Biophysics, and the Director of the Institute for Computational Biomedicine at Weill Cornell Medical College of Cornell University in New York City.
George Khelashvili, Ph.D. – Weill Cornell Medicine – …
Khelashvili, G, Cheng, X, Falzone, ME, Doktorova, M, Accardi, A, Weinstein, H et al.. Membrane lipids are both the substrates and a mechanistically responsive environment of TMEM16 scramblase proteins. J Comput Chem. 2020;41 (6)
Angiogenic network formation in the developing …
Materials and methods Zebrafish Zebrafish (Danio rerio) embryos were obtained from natural spawnings of laboratory lines.Embryos were raised and fish maintained as described (Kimmel et al., 1995; Westerfield, 1995).The Tg(fli1:EGFP) y1 transgenic zebrafish line used in this study has been described elsewhere (Lawson and Weinstein, 2002).